A 50 yr old female with AKI secondary to leptospirosis

 

A 50-year-old female patient who is a farmer by occupation and a resident of nakrekal came to the casualty with the cheif complaints of fever and swelling of both the legs since 3 days.


HISTORY OF PRESENT ILLNESS :

patient was apparently asymptomatic by 5 days back, then she developed fever which was insidious in onset intermittent in nature, assosiated with Chills and rigors and subsided on using medication (dolo) and increases during night time around 4 AM 


5 days before developing fever she had travelled intensely to and fro from her house. Inspite of raining on few days, she continued her travel and had also been working at her farm.


On the next day of onset of fever she visited a local hospital, where she got to know that she has jaundice, kidney infection and decreased platelet count and the doctors over there referred the patients to our hospital.


She had history of constipation for 2 yrs and passes stools once every 3 days. She said to get a relief from her constipation she consumed ajwain (vamu).


She had history of 4 episodes of loose stools 5 days back after consuming ajwain, which were non-blood stained and mucus was present. She suffered with a dragging type of pain in her abdomen after passing those stools which lasted for half an hr.


There is history of pedal edema which was gradual and assosiated with onset of fever and has decreased since 2 days.


She has a history of 3 episodes of vomiting 2 days back, which had food as its content.


She complained of a dragging type of pain from below her waist to her feet which only noticed when she moved her legs.


Bilateral pedal edema since 3 days Non pitting type


Burning micturition present


No history of shortness of breath



HISTORY OF PAST ILLNESS :

Not a known case of, 

Hypertension, diabetes, epilepsy, CAD, asthma, thyroid.


PERSONAL HISTORY :

Diet - mixed

Appetite - decreased 

sleep - inadequate

Bowel and Bladder movements - regular

Addictions - occasional toddy consumption 

No known allergies


DRUG HISTORY : 

No significant drug history


FAMILY HISTORY :

No significant family history


GENERAL EXAMINATION :

Patient is conscious ,coherent ,cooperative and was well oriented to time ,place and person 

at the time of examination

She is examined in a well lit room, with consent taken.

She is moderately built and well nourished.

Pallor - absent

Icterus - present

Icterus on inspection -

Cyanosis - absent 

Clubbing - absent

lymphadenopathy - absent

Pedal edema - present

Pedal edema on inspection -



Vitals : on the day of admission 

Temperature - Afebrile

Pulse rate - 96 bpm

Respiratory rate - 16 cpm

Blood pressure - 120/70 mmHg

SpO2 - 98% on Room air

GRBS - 101 mg/dl


SYSTEMIC EXAMINATION :

CVS :- S1 and S2 heart sounds heard

           NO murmurs and thrills

RESPIRATORY SYSTEM :- Bilateral air entry present position of trachea - centrall

           Vesicular breathsounds heard

CNS :- intact

ABDOMEN :- Soft and non tender

            No palpable masses

            Bowel sounds heard 

            NO organomegaly


INVESTIGATIONS :

On the day of admission 

Serum creatinine - 3.8 mg/dl (0.6 - 1.1)

Blood urea - 138 mg/dl (12 - 42)

Liver function test (lft):-
Total bilirubin:- 5.89
Direct bilirubin:- 2.10
SGOT(AST):- 719
SGPT(ALT):- 769
ALKALINE PHOSPHATE:- 155
TOTAL PROTEINS:-5.1
ALBUMIN:- 2.8

Hemogram - 
Haemoglobin - 6.9 gm/dl ( 12 to 15)
Total count - 10,900 cell/ cumm (4000 - 10000)
Lymphocytes - 14 % (20 - 40)
PCV - 19.6 (36 - 46)
Rbc - 2.36 mill/ cumm ( 3.8 to 4.8)


Dengue NS1 antigen , IgG and IgM rapid test - negative

Blood grouping - A positive



TREATMENT:

1.IVF - ns, RL @75ml/hr
2.Tab. Pan 40mg PO/OD
3.Tab. Zofer 4mg PO/ BD
4.Tab. paracetamol 650mg PO/TID
5.INJ. Neomol IV / SOS if temp >102°
6Temperature monitoring 4th hourly
7.Strict vitals monitoring - BP,PR 2nd hourly


PROVISIONAL DIAGNOSIS:

Fever with thrombocytopenia under evaluation 

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